Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia

Table 2

Comparison of blood glucose and pancreatic islet function among study groups.

Variable	SPK ()	RT ()	CRF ()	CON ()
Blood glucose (mmol/L), median (IQR)	5.0 (5.6-5.2)	6.1 (5.4–7.3)^##	7.7 (6.9, 8.8)^##	4.0 (3.8-4.3)^##	<0.001
Glycosylated hemoglobin (%), median (IQR)	4.8 (4.2-5.2)	7.3 (6.7–8.3)^##	7.5 (6.7–8.8)^##	4.2 (4.0-5.0)	<0.001
Insulin (μIU/mL), median (IQR)	6.8 (5.8–8.3)	4.8 (4.0-5.3)^##	5.3 (3.6–6.4)^##	7.7 (6.0–8.8)	<0.001
C-peptide (ng/mL), median (IQR)	4.2 (3.6–6.5)	3.4 (2.9-3.5)^##	3.4 (2.5–4.0)^##	4.7 (4.3-5.7)	<0.001
FPE (μg/g), median (IQR)	479 (335–557)	197 (185–502)^#	229 (163–457)^##	441 (341–554)	0.003
<200 μg/g (%)	1 (5.3)	12 (54.5)	14 (45.2)	1 (5.0)	<0.001
≧200 μg/g (%)	18 (94.7)	20 (45.5)	17 (54.8)	19 (95.0)

Comparison among four groups; ^#compared with the SPK group, ; ^##compared with the SPK group, . SPK: simultaneous pancreas–kidney transplantation; CRF: diabetic patients with uremia (chronic renal failure); RT: diabetic patients with uremia who underwent renal transplantation; CON: normal individuals; FPE: fecal pancreatic elastase.