Androgen Receptor Localizes to Plasma Membrane by Binding to Caveolin-1 in Mouse Sertoli Cells

Figure 4

2-Bromopalmitate prevented AR translocation to membrane. (a) Representative Western blot images showing AR transport in the membrane and nuclear fraction proteins from cells preincubated with vehicle (DMSO) or 2-bromopalmitate for 2 h before exposure to 10 nM testosterone. (b) Pooled data from 3 individual experiments. Data are expressed as mean ± SEM, and the values are calculated from the fold change of DMSO basal. The concentration of 2-bromopalmitate used in this study is 50 μM. .

(a)

(b)