International Journal of Endocrinology / 2017 / Article / Tab 2

Research Article

Therapeutic Outcomes of Patients with Multifocal Papillary Thyroid Microcarcinomas and Larger Tumors

Table 2

Clinical features of multifocal papillary thyroid cancer in different tumor sizes.

Clinical characteristicsAll patientsTumor Tumor value

Patient number626 (100.0)147 (23.5)479 (76.5)
Gender, female499 (79.7)116 (78.9)383 (80.0)0.783
Age at diagnosis (year)46.5 ± 13.547.1 ± 11.446.3 ± 14.10.541
355 (56.7)90 (61.2)265 (55.3)0.207
1-month postoperative serum Tg level (ng/mL)184.2 ± 1551.1296.5 ± 2725.5150.3 ± 941.60.331
Operative method
 Total thyroidectomy595 (95.0)130 (88.4)465 (97.1)<0.001
TNM stage
 Stage I390 (62.3)122 (83.0)268 (55.9)<0.001
 Stages II–IV236 (37.7)25 (17.0)211 (44.1)
Nonremission131 (20.9)18 (12.2)113 (23.6)0.003
 Residual83 (13.3)13 (8.8)70 (14.6)0.071
 Relapsed48 (7.7)5 (3.4)43 (9.0)0.026
Follow-up period (year)7.1 ± 5.36.6 ± 5.17.2 ± 5.40.245
Postoperative 131I accumulative dose (mCi) [range]153.7 ± 222.2 [0.0–2050.0]114.3 ± 176.7 [0.0–1350.0]165.9 ± 233.0 [0.0–2050.0]0.014
569 (90.9)127 (86.4)442 (92.3)0.030
57 (9.1)20 (13.6)37 (7.7)
Radiation therapy28 (4.5)5 (3.4)23 (4.8)0.472
2nd primary cancer49 (7.8)11 (7.5)38 (7.9)0.859
Diabetes mellitus61 (9.7)12 (8.2)49 (10.2)0.460
Overall mortality49 (7.8)8 (5.4)41 (8.6)0.218
Cancer mortality25 (4.0)4 (2.7)21 (4.4)0.368
Disease-free221 (35.3)58 (39.5)163 (34.0)0.228
Lymph node metastasis197 (31.5)33 (22.4)164 (34.2)0.007
Soft tissue invasion153 (24.4)14 (9.5)139 (29.0)<0.001
Distant metastasis39 (6.2)5 (3.4)34 (7.1)0.105

Number (%); mean ± SD.

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