Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China
Table 1
Characteristics of the participants by quartiles of total testosterone.
Total testosterone, nmol/L
Q1
Q2
Q3
Q4
for trend
≤12.60
12.61–15.70
15.71–19.91
≥19.92
N
1094
1059
1072
1075
Age, yr
53 (13)
52 (13)
53 (14)
58 (13)
<0.001
Body mass index, kg/m2
26.3 (3.4)
25.2 (3.1)
24.5 (3.1)
23.3 (3.1)
<0.001
Waist circumference, cm
87.8 (9.6)
85.1 (9.1)
83.4 (9.4)
81.0 (9.2)
<0.001
Neck circumference, cm
37.0 (3.6)
36.3 (3.4)
35.6 (3.2)
34.8 (2.6)
<0.001
Waist-hip ratio
0.91 (0.07)
0.89 (0.07)
0.89 (0.07)
0.88 (0.08)
<0.001
Triglycerides, mmol/L
2.66 (2.92)
1.95 (1.74)
1.62 (1.19)
1.28 (0.70)
<0.001
HDL, mmol/L
1.27 (0.31)
1.31 (0.30)
1.38 (0.32)
1.47 (0.32)
<0.001
LDL, mmol/L
3.11 (0.76)
3.06 (0.73)
3.10 (0.76)
3.06 (0.78)
0.40
Total cholesterol, mmol/L
5.26 (1.22)
5.12 (1.17)
5.14 (1.08)
5.09 (0.98)
<0.01
Fasting plasma glucose, mmol/L
6.09 (1.88)
5.72 (1.45)
5.56 (1.44)
5.45 (1.10)
<0.001
HbA1c, mmol/L
5.8 (1.3)
5.6 (1.0)
5.6 (1.0)
5.5 (0.7)
<0.001
HOMA-IR
2.11 (3.24)
1.56 (3.73)
1.29 (1.97)
1.01 (1.20)
<0.001
Systolic blood pressure, mmHg
135 (20)
134 (20)
134 (21)
135 (22)
0.43
Diastolic blood pressure, mmHg
84 (13)
82 (12)
82 (13)
81 (13)
<0.001
Overweight, %
50.2
46.4
36.9
25.0
<0.001
Obesity, %
14.1
5.9
4.1
2.7
<0.001
Diabetes, %
23.1
15.4
12.6
9.5
<0.001
Hypertension, %
56.3
51.2
49.3
51.4
<0.05
Dyslipidemia, %
62.6
43.3
38.7
26.0
<0.001
Metabolic syndrome, %
37.9
24.2
20.7
11.5
<0.001
The data are summarized as the mean (standard deviation) for continuous variables or as a number with proportion for categorical variables. for trend was calculated by ANOVA and Chi-square test.