Testosterone: Relationships with Metabolic Disorders in Men—An Observational Study from SPECT-China
Table 2
Subgroup association of total testosterone with metabolic diseases.
(a)
Age category
Smoking status
<60
≥60
for interaction
Nonsmoking
Smoking
for interaction
Overweight
0.58 (0.52, 0.65)
0.58 (0.51, 0.66)
0.37
0.61 (0.55, 0.68)
0.53 (0.47, 0.60)
0.02
Obesity
0.39 (0.33, 0.46)
0.43 (0.36, 0.53)
0.81
0.45 (0.38, 0.53)
0.36 (0.30, 0.43)
0.03
Central obesity
0.61 (0.55, 0.68)
0.59 (0.52, 0.67)
0.72
0.69 (0.62, 0.76)
0.54 (0.48, 0.60)
<0.001
Diabetes
0.71 (0.62, 0.80)
0.70 (0.61, 0.80)
0.61
0.65 (0.58, 0.74)
0.76 (0.67, 0.87)
0.28
Hypertension
0.88 (0.80, 0.97)
0.94 (0.83, 1.06)
0.27
0.92 (0.83, 1.02)
0.88 (0.79, 0.99)
0.88
Dyslipidemia
0.62 (0.56, 0.69)
0.71 (0.63, 0.80)
0.40
0.70 (0.63, 0.77)
0.60 (0.54, 0.68)
0.02
Metabolic syndrome
0.56 (0.50, 0.62)
0.53 (0.46, 0.60)
0.46
0.64 (0.57, 0.71)
0.46 (0.40, 0.52)
<0.001
(b)
Economic status
Weight status
Low
High
for interaction
BMI <25 kg/m2
BMI ≥25 kg/m2
for interaction
Overweight
0.57 (0.50, 0.64)
0.58 (0.52, 0.65)
0.24
Obesity
0.38 (0.31, 0.46)
0.42 (0.35, 0.50)
0.27
Central obesity
0.61 (0.55, 0.69)
0.59 (0.53, 0.66)
0.53
Diabetes
0.70 (0.60, 0.80)
0.70 (0.63, 0.79)
0.63
0.70 (0.62, 0.79)
0.65 (0.57, 0.74)
0.48
Hypertension
0.91 (0.81, 1.03)
0.89 (0.81, 0.98)
0.40
0.87 (0.79, 0.96)
0.82 (0.73, 0.93)
0.46
Dyslipidemia
0.68 (0.60, 0.77)
0.64 (0.57, 0.71)
0.85
0.62 (0.55, 0.69)
0.61 (0.54, 0.69)
0.87
Metabolic syndrome
0.51 (0.45, 0.58)
0.56 (0.50, 0.63)
0.27
Adjusted ORs for each one SD increment of ln-total testosterone associated with metabolic diseases. The data are expressed as odds ratio (95% confidence interval). Logistic regression analysis was used. Model controls for age, smoking, economic status, and body mass index (not for obesity indices and metabolic syndrome).
