Research Article

Central Precocious Puberty and Response to GnRHa Therapy in Children with Cerebral Palsy and Moderate to Severe Motor Impairment: Data from a Longitudinal, Case-Control, Multicentre, Italian Study

Table 1

Baseline features of groups A, B, and C.

Group AGroup BGroup C

Num. (F/M)22 (18/4)22 (17/5)22 (22/0)
Baseline age (years) (mean ± SDS; range)6.42 ± 1.74 (2.74–8.90)6.63 ± 1.85 (2.10–9.70)7.02 ± 0.79 (5.20–7.96)
Gestational age (weeks) (mean ± SDS)36.93 ± 4.6137.94 ± 4.1139.33 ± 0.70
Apgar 1 min (mean ± SDS)°4.58 ± 3.023.23 ± 2.249.01 ± 0.54
Apgar 5 min (mean ± SDS)°6.25 ± 2.565.00 ± 1.809.50 ± 0.22
Birth weight (kg) (mean ± SDS)2.65 ± 0.853.04 ± 0.843.33 ± 0.35°
GMFCS (III, IV, V) (%)68, 27, 573, 18, 9NA
Use of antiepileptic medication (%)77%100%0%

°Significant difference between groups A and C.