Research Article

Central Precocious Puberty and Response to GnRHa Therapy in Children with Cerebral Palsy and Moderate to Severe Motor Impairment: Data from a Longitudinal, Case-Control, Multicentre, Italian Study

Table 3

Longitudinal evaluation of biochemical data of patients with CPP at baseline (diagnosis of CPP) and during GnRHa treatment.

Baseline1st follow-up visit2nd follow-up visit
Group AGroup CGroup AGroup CGroup AGroup C

LH (mUI/ml)2.54 ± 2.230.49 ± 0.50^0.58 ± 0.560.28 ± 0.170.48 ± 0.550.28 ± 0.15
FSH (mUI/ml)5.34 ± 5.963.44 ± 1.411.86 ± 1.780.78 ± 0.572.65 ± 2.180.47 ± 0.25
Oestradiol (pg/ml)27.13 ± 16.9212.65 ± 6.94^12.36 ± 6.7211.93 ± 2.9411.13 ± 3.0211.28 ± 2.21

^Significant difference between the groups at the specific time point.