International Journal of Endocrinology / 2017 / Article / Tab 1

Review Article

The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause

Table 1

Targeted responses to systemic menopause treatments [611].

TargetSERMs
Ral, BZA
EstrogenSTEAR
(tibolone)
TSEC
(BZA/CE)

Uterus0=0
Hot flushes+++
Vagina+++
Bone++++
Breast+0=0
Sexual function=++++
Energy levels=++++

STERM: selective estrogen receptor modulator; Ral: raloxifene; BZA: bazedoxifene; STEAR: selective tissue estrogenic activity regulator (tibolone); TSEC: tissue selective estrogen complex = BZA + CE; +: positive effect; ++: very positive effect; −: negative effect; =: neutral effect.

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