Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy
Table 2
Characteristics of T2DM patients with the low, middle, and high serum ZAG levels.
ZAG (μg/ml)
Total
Low (0.57~1.19)
Median (1.19~1.52)
High (1.52~3.26)
Age (y)
<61
198 (45.2)
66 (45.5)
66 (44.9)
66 (45.2)
≥61
240 (54.8)
79 (54.5)
81 (55.1)
80 (54.8)
0.95
Gender
Men
151 (34.5)
36 (24.8)
60 (40.8)
55 (37.7)
Women
287 (65.5)
109 (75.2)
87 (59.2)
91 (62.3)
0.022
Education (y)
≤6
205 (46.8)
71 (49.0)
74 (50.3)
60 (41.1)
>6
233 (53.2)
74 (51.0)
73 (49.7)
86 (58.9)
0.18
BMI (kg/m2)
<24
61 (13.9)
16 (11.0)
18 (12.2)
27 (18.5)
≥24
377 (86.1)
129 (89.0)
129 (87.8)
119 (81.5)
0.066
WC (cm)
<90 (or 85)1
28 (6.4)
7 (4.8)
7 (4.8)
14 (9.6)
≥90 (or 85)
410 (93.6)
138 (95.2)
140 (95.2)
132 (90.4)
0.097
Hypertension2
None
302 (69.0)
92 (63.5)
105 (71.4)
105 (91.9)
Yes
136 (31.0)
53 (36.5)
42 (28.6)
41 (28.1)
0.12
TC (mmol/L)
<5.2
79 (18.0)
33 (22.8)
26 (17.7)
20 (13.7)
≥5.2
359 (82.0)
112 (77.2)
121 (82.3)
126 (86.3)
0.045
TG (mmol/L)
<1.7
307 (70.1)
109 (75.2)
102 (69.4)
96 (65.8)
≥1.7
131 (29.9)
36 (24.8)
45 (30.6)
50 (34.2)
0.080
HbA1C (%)
≤7.0
192 (43.8)
71 (49.0)
56 (38.1)
65 (44.5)
>7.0
246 (56.2)
74 (51.0)
91 (61.9)
81 (55.5)
0.45
FPG (mmol/L)
≤7.0
139 (31.7)
44 (30.3)
40 (27.2)
55 (37.7)
>7.0
299 (68.3)
101 (69.7)
107 (72.8)
91 (62.3)
0.18
uACR (mg/mmol)
<2.7
261 (59.6)
88 (60.7)
85 (57.8)
88 (60.3)
≥2.7
177 (40.4)
57 (39.3)
62 (42.2)
58 (39.7)
0.94
25OHD (nmol/L)
>50
135 (30.8)
25 (17.2)
60 (40.8)
50 (34.2)
≤50
303 (69.2)
120 (82.8)
87 (59.2)
96 (65.8)
0.0017
eGFR (ml/min)
≥90
176 (40.2)
64 (44.1)
65 (44.2)
47 (32.2)
<90
262 (59.8)
81 (55.9)
82 (55.8)
99 (67.8)
0.038
1WC defined as (<90, ≥90) in men and (<85, ≥85) in women, all units in cm. 2Hypertension defined as SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg, or self-reported use of an antihypertensive medication.
