Etiology of Hypopituitarism in Adult Patients: The Experience of a Single Center Database in the Serbian Population

Table 2

Characteristics of the most common causes of hypopituitarism in our database (TBI—trauma brain injury; SAH—subarachnoid hemorrhage; HFRS—hemorrhagic fever with renal syndrome caused by Hantavirus).

Cause of hypopituitarism	Age (mean ± SE)	Sex, males (N/%)	Number of deficient hormones (mean ± SE)
Nonfunctional adenoma	56.1 ± 0.9	123/59.1	2.5 ± 0.6
Congenital causes	30.2 ± 1.4	43/57.3	2.3 ± 0.1
GH adenoma	45.3 ± 2.3	21/56.8	2.3 ± 0.1
PRL adenoma	49.7 ± 2.0	26/72.2	1.8 ± 0.2
Craniopharyngioma	36.0 ± 2.6	17/56.7	2.7 ± 0.1
TBI + SAH	48.2 ± 2.7	16/59.3	1.1 ± 0.2
Extrapituitary cranial irradiation	28.6 ± 2.8	11/61.1	1.6 ± 0.1
HFRS	35.1 ± 2.0	18/100	1.5 ± 0.2