Research Article
Correlation between CH2DS2-VASc Score and Serum Leptin Levels in Cardioembolic Stroke Patients: The Impact of Metabolic Syndrome
Table 1
Baseline demographic, clinical, and laboratory characteristics of stroke cases and matched controls.
| | Cases () | Control () | p |
| | Gender, M/F | 47/52 | 30/29 | 0.68 | | Age, mean (SD), y | 70.7 (12.6) | 67.8 (10.2) | 0.06 | | Arterial hypertension (%) | 73 (73.7) | 34 (57.6) | <0.05 | | Diabetes/impaired glucose metabolism (%) | 24 (24.2) | 23 (39.0) | <0.05 | | Atrial fibrillation (%) | 46 (46.5) | 3 (5.1) | <0.001 | | Ischemic heart disease (%) | 28 (28.3) | 9 (15.3) | 0.06 | | Congestive heart failure (%) | 8 (8.1) | 1 (1.7) | 0.09 | | Ischemic stroke/TIA | 22 (22.2) | — | — | | Hypercholesterolemia (%) | 19 (19.2) | 11 (18.6) | 0.96 | | Peripheral vascular disease (%) | 5 (5.1) | — | — | | Current smoker (%) | 27 (27.6) | 12 (20.7) | 0.34 | | Past smoker (%) | 33 (52.4) | 15 (26.3) | <0.01 | | Current drinker (%) | 12 (13.0) | 3 (5.1) | 0.11 | | Metabolic syndrome (%) | 50 (50.5) | 30 (50.8) | 0.97 | | ACE-1/AT-II (%) | 57 (57.6) | 27 (45.8) | 0.15 | | Statins (%) | 16 (16.3) | 10 (16.9) | 0.92 | | BMI (kg/m2) | 27.5 (5.3) | 26.3 (4.2) | 0.18 | | Waist circumference (cm) | 95.2 (15.5) | 95.9 (13.2) | 0.71 | | Fasting serum glucose level, mg/dl (SD) | 125.1 (34.8) | 100.5 (21.7) | <0.001 | | Blood white cell count, ×109/l (SD) | 8.2 (2.6) | 6.2 (1.9) | <0.001 | | Blood platelet count, ×109/l (SD) | 23.3 (8.1) | 24.3 (6.8) | 0.26 | | Hematocrit (%) | 41.52 (7.9) | 40.57 (4.0) | 0.30 | | Total cholesterol, mg/dl (SD) | 192.1 (49.2) | 204.9 (40.4) | 0.06 | | Triglycerides, mg/dl (SD) | 124.6 (67.3) | 136.5 (72.7) | 0.11 | | LDL-cholesterol, mg/dl (SD) | 118.7 (40.1) | 125.2 (33.1) | 0.16 | | HDL-cholesterol, mg/dl (SD) | 47.2 (16.2) | 51.2 (13.5) | <0.05 | | Creatinine, mg/dl (SD) | 0.98 (0.3) | 0.8 (0.3) | <0.001 | | Uric acid, mg/DL (SD) | 5.5 (1.5) | 5.5 (1.7) | 0.53 | | hs.C-reactive protein, mg/dl (SD) | 9.5 (15) | 2.8 (3.5) | <0.001 | | Fibrynogen, g/L | 3.7 (1.2) | 3.3 (0.7) | <0.05 | | ALT, U/L (SD) | 23.8 (10.4) | 26.7 (20.3) | 0.89 | | ASPAT,U/L(SC) | 31.9 (16.7) | 25.4 (7.6) | <0.01 | | Adiponectin, μg/mL (SD) | 12.8 (10.0) | 12.5 (9.7) | 0.62 | | Resistin, μg/mL (SD) | 7.0 (3.6) | 6.9 (2.9) | 0.55 | | Leptin, μg/mL (SD) | 15.9 (16.5) | 17.4 (14.6) | 0.25 |
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