Clinical Study

Empagliflozin Increases Short-Term Urinary Volume Output in Artificially Induced Syndrome of Inappropriate Antidiuresis

Table 2

Number of participants who experienced symptoms attributable to hyponatremia during the study with the according average score of symptom severity on visual analogue scale in brackets (range 0 = no symptoms to 10 = severe symptoms).

SymptomsEmpagliflozinPlacebo

Thirst9 (2.4)7 (2.9)0.51
Headache10 (2.4)11 (1.7)0.75
Nausea7 (3.1)6 (3.0)0.67
Vertigo6 (2.6)3 (2.5)0.50
General malaise7 (2.8)5 (3.0)0.94