Research Article

Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain

Table 4

Single time-point plasma glucose level (mM), mean ± SD.

GroupnDay 8a (difference from control)nDay 29 (difference from control)nDay R2 (difference from control)nDay R29b

CTRL-M369.20 ± 1.0678.57 ± 0.31777.52 ± 0.652108.47 ± 0.75
HI-M356.24 ± 3.19 (−32%)84.30 ± 1.883 (−50%)616.10 ± 7.855 (+114%)59.83 ± 1.74
CTRL-F379.05 ± 0.8289.01 ± 0.70068.19 ± 1.00398.42 ± 0.62
HI-F376.15 ± 2.74 (−32%)84.84 ± 1.394 (−46%)69.55 ± 1.401#98.75 ± 1.04

a6 h time point. b0.25 h time point. and versus control; # versus HI-M.