Metabolomic Signature of Coronary Artery Disease in Type 2 Diabetes Mellitus

Table 2

ORs for the selected metabolites using logistic regression analysis in 57 T2D patients. Independent variables used in multiple logistic regression analysis: sex, age, BMI, HbA1c, diabetes duration, SBP, DBP, antihypertensive, triacylglycerols, LDL : HDL ratio, lipid-lowering agents, albumin, and eGFR. ORs are presented as change in concentrations per one SD.

Metabolite	CAD; Mean ± SD	Non-CAD; Mean ± SD	OR (95% CI)	value
C0	52.17 ± 15.94	42.46 ± 11.72	6.97 [1.70; 61.93]	0.026
Serine	86.05 ± 18.89	99.92 ± 20.37	0.15 [0.01; 0.70]	0.045
PC aa C36:1	38.95 ± 9.40	50.84 ± 12.23	0.16 [0.02; 0.60]	0.020
PC aa C38:3	48.11 ± 13.40	64.26 ± 16.64	0.21 [0.04; 0.81]	0.045