Clinical Study
Thyroid Cancer in Saudi Arabia: A Histopathological and Outcome Study
Table 5
Univariate and multivariate analyses of demographic and histopathological predictive factors for the outcome at the last follow-up visit.
| Outcome at final follow-up | Unadjusted | Adjusted | Characteristic | Remission | Persistent/recurrent disease | value | Odds ratio (95% CI) | value |
| Male gender | 52/318 (16.4%) | 80/225 (31.4%) | <0.0001 | 1.48 (0.64–3.4) | 0.36 | Age at diagnosis (yrs) | 36.7 ± 12.9 | 43.5 ± 15.6 | <0.0001 | 1.039 (1.012–1.07) | 0.005 | Tumor size (cm) | 3.3 ± 2.3 | 3.4 ± 2.4 | 0.84 | | | Tumor multifocality | 143/272 (52.6%) | 92/186 (49.5%) | 0.58 | | | Extrathyroidal extension | 85/258 (32.9%) | 115/199 (57.8%) | <0001 | 3.26 (1.43–7.42) | 0.005 | Lymphovascular invasion | 29/110 (26.4%) | 39/77 (50.6%) | 0.001 | 1.52 (0.69–3.34) | 0.30 | Lymph node metastasis | 128/313 (40.9%) | 143/248 (57.7%) | <0.0001 | 1.11 (0.51–2.43) | 0.79 | Distant metastasis | 19/316 (6%) | 55/248 (22.2%) | <0.0001 | 2.11 (0.77–5.78) | 0.15 |
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