Serum Osteoprotegerin Is a Potential Biomarker of Insulin Resistance in Chinese Postmenopausal Women with Prediabetes and Type 2 Diabetes

Table 3

Bivariate correlation analysis between study parameters and serum osteoprotegerin levels.

Parameters	Bivariate correlation
	r	value
Age	0.453	<0.001
Height	−0.115	0.058
Weight	−0.082	0.178
BMI	−0.036	0.552
Waist circumference	0.078	0.203
Hip circumferences	−0.005	0.793
Waist-to-hip ratio	0.125	0.039
Body fat percentage	0.213	<0.001
ALT	−0.014	0.823
AST	0.086	0.157
ALP	0.175	0.004
BUN	0.025	0.688
Cr	0.193	0.001
Calcium	−0.001	0.981
URCA	0.046	0.451
TC	−0.006	0.924
TG	0.027	0.660
HDL-C	0.012	0.847
LDL-C	−0.077	0.207
FPG	0.093	0.133
2hPG	0.270	<0.001
HbA1c	0.214	<0.001
FINS	0.106	0.080
Ln HOMA-IR	0.134	0.027
HOMA-B	−0.037	0.546
QUICKI	−0.194	0.001
eGFR	−0.331	<0.001
Lumbar BMD	−0.189	0.002
Femoral neck BMD	−0.130	0.032

2hPG, 2 h postprandial plasma glucose; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMD, bone mineral density; BMI, body mass index; BUN, blood urea nitrogen; Cr, creatinine; eGFR, estimate glomerular filtration rate; FINS, fasting insulin; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; HOMA-B, homeostasis model assessment of β-cell function; LDL-C, low-density lipoproteincholesterol; Ln HOMA-IR, natural logarithmic transformation homeostasis model of assessment for insulin resistance index; OPG, osteoprotegerin; QUICKI, quantitative insulin sensitivity check index; SBP, systolic blood pressure; SDP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; URCA, blood uric acid.