Expression of Somatostatin Receptor 2 in Somatotropinoma Correlated with the Short-Term Efficacy of Somatostatin Analogues

Table 1

Basic characteristics of the cohorts.

	Entire cohort	DS group	SA group	value
Number (female/male)	93 (59/34)	30 (20/10)	63 (39/24)	0.82^a
Age at diagnosis, y				0.59^b
GH, μg/L	34.2 (13.5–57.9)	26.4 (12.1–66.5)	40.9 (15.7–56.1)	0.22^c
IGF-1 index	2.9 (2.4–3.6)	2.4 (1.9–2.8)	3.0 (2.6–3.6)	<0.01^c
Adenoma volume (), mm^3	1900 (1000–2515)	1470 (249–6160) ()	2110 (1000–2500) ()	0.65^c

DS, direct surgery group; SA, pretreatment with somatostatin analogues before surgery; GH, growth hormone; IGF-1, insulin-like growth factor 1. Data are mean ± SEM for age at diagnosis and median with interquartile range for GH, IGF-1 index, and adenoma volume. For adenoma volume, there are 77 patients available for analysis (for DS group, , while for SA group, ). ^aΧ² test. ^bStudent’s t-test. ^cStudent’s t-test after log transformation.