Thyroid Imaging Reporting and Data System Score Combined with the New Italian Classification for Thyroid Cytology Improves the Clinical Management of Indeterminate Nodules

Table 1

Demographic, ultrasonographic, cytological, and histological parameters of 70 patients affected by indeterminate thyroid lesions. TI-RADS, thyroid imaging reporting and data system; FTC, follicular thyroid cancer; FA, follicular adenoma; CV-PTC, classical variant of papillary thyroid carcinoma; FV-PTC, follicular variant of papillary thyroid carcinoma; NH, nodular hyperplasia; CLT, chronic lymphocytic thyroiditis; WDT-UMP, well-differentiated tumor-uncertain malignant potential; HA, Hürthle adenoma. Nodule volume is expressed in milliliters.

Number	Sex	Age	Nodule volume	SIAPEC 2007	SIAPEC 2014	Nodule histological diagnosis	TI-RADS score
1	M	20	2.268	TIR3	TIR3B	FTC	4c
2	F	24	0.252	TIR3	TIR3A	FA	4c
3	F	28	4.18	TIR3	TIR3A	CV-PTC	4c
4	F	35	0.432	TIR3	TIR3A	FV-PTC	4c
5	M	36	0.99	TIR3	TIR3A	NH	4c
6	F	41	0.495	TIR3	TIR3B	CV-PTC	5
7	F	42	1.607	TIR3	TIR3B	NH	4b
8	F	43	0.45	TIR3	TIR3B	CV-PTC	4c
9	F	50	0.243	TIR3	TIR3B	CV-PTC	4c
10	M	52	2.2	TIR3	TIR3A	NH	4b
11	M	54	1.296	TIR3	TIR3A	NH	4b
12	F	55	2.66	TIR3	TIR3B	NH	4b
13	F	55	4.9	TIR3	TIR3A	NH	4a
14	F	58	1.26	TIR3	TIR3A	FA	4c
15	M	58	4.568	TIR3	TIR3A	NH	3
16	F	61	0.18	TIR3	TIR3B	NH	4c
17	F	62	3.658	TIR3	TIR3A	NH	4c
18	F	64	0.99	TIR3	TIR3A	CLT	3
19	F	66	1.08	TIR3	TIR3A	NH	4c
20	F	68	0.096	TIR3	TIR3B	CV-PTC	4c
21	F	69	0.2	TIR3	TIR3B	NH	4b
22	F	69	0.792	TIR3	TIR3A	WDT-UMP	4c
23	F	72	1.08	TIR3	TIR3A	FA	4b
24	F	75	3.12	TIR3	TIR3B	CV-PTC	4b
25	F	52	0.123	TIR3	TIR3B	NH	4c
26	F	63	2.025	TIR3	TIR3B	NH	4a
27	F	64	0.264	TIR3	TIR3B	CV-PTC	4b
28	F	73	0.49	TIR3	TIR3A	NH	4c
29	M	57	0.756	TIR3	TIR3B	CV-PTC	4b
30	F	60	0.484	TIR3	TIR3B	NH	4b
31	M	40	1.344	TIR3	TIR3B	NH	4a
32	F	57	0.24	TIR3	TIR3A	NH	4b
33	M	32	1.08	TIR3	TIR3B	NH	4a
34	F	45	0.196	TIR3	TIR3B	FV-PTC	4c
35	F	13	0.576	TIR3	TIR3A	NH	4c
36	F	27	8.58	TIR3	TIR3A	NH	4a
37	F	46	0.168	TIR3	TIR3B	CV-PTC	4c
38	F	58	2.04	TIR3	TIR3B	FA	4b
39	M	56	3.105	TIR3	TIR3B	NH	4a
40	F	63	0.75	TIR3	TIR3A	NH	4a
41	F	67	4.774	TIR3	TIR3B	FA	4b
42	M	49	0.364	TIR3	TIR3B	FV-PTC	4b
43	F	56	0.216	TIR3	TIR3B	CV-PTC	4c
44	F	64	0.96	TIR3	TIR3A	NH	4a
45	M	64	1.53	TIR3	TIR3B	NH	4b
46	F	73	1.755	TIR3	TIR3B	NH	4a
47	F	42	1.19	TIR3	TIR3A	NH	4c
48	F	77	2.7	TIR3	TIR3B	NH	4b
49	F	68	7.038	TIR3	TIR3A	FTC	4a
50	M	65	1.615	TIR3	TIR3A	FA	4c
51	F	70	0.88	TIR3	TIR3A	HA	4b
52	M	40	10.93	TIR3	—	NH	4b
53	F	63	1.02	TIR3	—	NH	4a
54	F	31	12.18	TIR3	—	NH	3
55	F	50	1.836	TIR3	—	NH	3
56	F	63	2.432	TIR3	—	NH	4a
57	F	66	1.224	TIR3	—	NH	4c
58	M	16	0.32	TIR3	—	FA	4a
59	M	24	1.368	TIR3	—	FA	4c
60	M	69	0.825	TIR3	—	NH	4b
61	F	43	0.336	TIR3	—	NH	4b
62	F	71	0.833	TIR3	—	NH	4b
63	F	40	2.835	TIR3	—	NH	4a
64	M	59	0.216	TIR3	—	CV-PTC	4c
65	F	70	0.41	TIR3	—	NH	4b
66	M	65	0.462	TIR3	—	FA	4c
67	F	36	0.16	TIR3	—	NH	3
68	F	39	0.484	TIR3	—	NH	4a
69	F	56	0.672	TIR3	—	CV-PTC	4c
70	F	67	4.641	TIR3	—	FA	3