Changes in the Responsiveness of the Hypothalamic-Pituitary-Gonadal Axis to Kisspeptin-10 Administration during Pubertal Transition in Boys

Table 1

Anthropometric and genital data of all the Tanner groups and adult men.

Groups	Tanner I	Tanner II	Tanner III	Tanner IV	Tanner V	Adult
Age (years)	7.06 ± 0.19	9.6 ± 0.61	11.9 ± 0.55	14 ± 0.16	15.5 ± 0.22	25.80 ± 0.37
Body weight (kg)	20.2 ± 1.01	26 ± 1.18	29.60 ± 1.63	37.40 ± 1.24	56.4 ± 2.29	61.20 ± 1.15
Height (foot and inch)	3.62 ± 0.13	4.3 ± 0.10	4.4 ± 0.09	5 ± 0.15	5.46 ± 0.06	5.54 ± 0.08
Waist (inch)	22.4 ± 0.39	24 ± 0.54	25 ± 0.54	27.8 ± 0.73	31.1 ± 1.14
BMI (kg/m^2)	17.33 ± 0.71	15.47 ± 0.25	16.95 ± 0.72	18.93 ± 1.31	21.04 ± 1.09	22.06 ± 0.63
Penile length (cm)	3.06 ± 0.11	3.8 ± 0.20	4.06 ± 0.31	4.6 ± 0.36	7.6 ± 0.59
Total testicular volume (ml)	2.51 ± 0.84	2.68 ± 0.72	5.04 ± 1.71	6.12 ± 1.73	23.28 ± 0.97
Pubic hair	VH	SD	PH	HD	HD
Scrotum	SS	ER	IG	DD	SC

VH = vellus hair appears over the pubes; SS = scrotal sac has a size and proportion similar to those seen in early childhood; SD = sparse development of long pigmented downy hairs especially at the base of the penis; ER = enlargement and reddening of the scrotum; PH = pubic hair is considerably darker, curlier, and coarser. These hairs spread over the junction of pubes; IG = increased growth of the scrotum; HD = hair distributions are of adult type but they do not spread to the medial surface of thighs; DD = distinct darkening of the scrotal skin; HD = hair distributions in adult both in quantity and type. They can spread to the medial surface of thigh and are described in the inverse triangle; SC = the scrotums are of adult type with regard to shape and size.