Clinical Study
Melatonin Treatment Improves Insulin Resistance and Pigmentation in Obese Patients with Acanthosis Nigricans
| Parameters | Baseline | After 12 weeks of treatment | value |
| SBP, mmHg | 134.18 ± 10.690 | 131.88 ± 10.787 | 0.085 | DBP, mmHg | 87.53 ± 10.967 | 87.00 ± 11.292 | 0.478 | HR, bmp | 85.35 ± 7.533 | 82.35 ± 9.096 | 0.174 | Weight, kg | 100.912 ± 22.9884 | 97.453 ± 21.8012 | 0.001 | Body fat, % | 37.206 ± 5.3743 | 35.488 ± 6.6078 | 0.038 | BMI, kg/m2 | 35.741 ± 4.7844 | 34.524 ± 4.7278 | 0.001 | Visceral index | 17.41 ± 6.510 | 15.82 ± 6.085 | 0.001 | NC, cm | 40.718 ± 4.1652 | 40.118 ± 4.1213 | 0.045 | WC, cm | 111.471 ± 13.7184 | 107.853 ± 14.2607 | 0.002 | HC, cm | 114.818 ± 10.6647 | 113.488 ± 10.5441 | 0.028 | AN score, neck | 3.35 ± 0.862 | 2.59 ± 0.712 | <0.01 | AN score, axilla | 3.53 ± 0.717 | 2.65 ± 0.702 | <0.01 |
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