The Combined Effect of Nonalcoholic Fatty Liver Disease and Metabolic Syndrome on Osteoporosis in Postmenopausal Females in Eastern China

Table 3

Measures for estimation of biological interaction between MetS and SNAFLD for the risk of osteoporosis in postmenopausal females.

	Total number	Total case	value	OR (95% CI)	value
MetS (−) SNAFLD (−)	641	126 (19.7)	<0.001^a	1.0
MetS (−) SNAFLD (+)	64	24 (37.5)	0.023^b	2.132 (1.166–3.900)	0.011
MetS (+) SNAFLD (−)	164	54 (34.1)	<0.001^c	1.945 (1.162–3.253)	0.031
MetS (+) SNAFLD (+)	68	40 (58.8)		5.632 (3.281–9.666)	0.001
Measures of biological interaction		Estimate (95% CI)
RERI		2.556 (0.475–4.636)
AP		0.454 (0.201–0.706)
SI		2.231 (1.124–4.428)

SNAFLD: significant nonalcoholic fatty liver disease; MetS: metabolic syndrome. Note: data are expressed as (%); represents the value ≤ 0.05. value represents MetS (+) SNAFLD (+) versus MetS (−) SNAFLD (−); value represents MetS (+) SNAFLD (+) versus MetS (−) SNAFLD (+); value represents MetS (+) SNAFLD (+) versus MetS (+) SNAFLD (−).