Value of Apoptotic, Antiapoptotic, and Cell Proliferation Markers in the Treatment of Graves’ Disease

Table 3

Expression of proliferation markers in thyrocytes and lymphocytes in patients with Graves’ disease according to the type of treatment (chi-square test/Fisher’s exact test).

Markers	Cells		ATD (%)	Without ATD (%)	RIT (%)	Beta-blocker (%)
Ki-67	Thyrocytes	<1%	56.82	25	83.33	62.16
		>1%	43.18	75	16.67	37.84
		value	0.1337		0.1919	0.0385
	Lymphocytes	<1%	38.64	37.5	66.67	45.95
		>1%	61.36	62.5	33.33	54.05
		value	1.0		0.1710	0.0608
p27	Thyrocytes	<25%	18.18	50	50	29.73
		>25%	81.82	50	50	70.27
		value	0.0715		0.1480	0.1433
	Lymphocytes	<25%	63.64	37.5	100	64.86
		>25%	36.36	62.5	0	35.14
		value	0.4115		0.0445	0.4798