Serum Matrix Metalloproteinase 9 and Macrophage Migration Inhibitory Factor (MIF) Are Increased in Young Healthy Nonobese Subjects with Positive Family History of Type 2 Diabetes

Table 1

Clinical and biochemical characteristics of the study groups.

	Control; ()	Family history of type 2 diabetes; ()
Age (years)	22.96 ± 2.36	22.79 ± 2.21
BMI (kg/m^2)	23.89 ± 2.70	24.33 ± 2.87
Waist (cm)	84.35 ± 8.16	85.76 ± 8.95
% body fat	20.76 ± 7.42	18.98 ± 7.73
Fasting glucose (mg/dl)	86.29 ± 8.04	87.19 ± 9.33
Fasting insulin (μIU/ml)	10.03 ± 4.32	12.60 ± 8.31
(mg/kgffm/min)	7.76 ± 3.02	6.36 ± 1.83
Cholesterol (mg/dl)	167.58 ± 31.10	170.13 ± 33.78
TG (mg/dl)	79.97 ± 38.32	96.41 ± 50.77
HDL cholesterol (mg/dl)	61.73 ± 11.55	67.53 ± 12.68
LDL cholesterol (mg/dl)	96.59 ± 31.13	101.27 ± 35.82
hsCRP (mg/l)	0.56 ± 0.49	0.50 ± 0.47
IL-18 (pg/ml)	247.73 ± 84.18	240.64 ± 58.60
MCP-1 (pg/ml)	356.59 ± 141.85	370.88 ± 151.35
MIC-1 (pg/ml)	365.77 ± 112.90	356.31 ± 113.36
sE-selectin (ng/ml)	34.25 ± 14.73	36.62 ± 14.11
sVCAM (ng/ml)	792.09 ± 167.12	732.64 ± 173.61
sICAM (ng/ml)	230.30 ± 46.51	226.55 ± 41.83

Data are presented as mean ± SD; .