Peripheral Arterial Disease in Type 2 Diabetes Is Associated with an Increase in Fibrinogen Levels

Table 2

Baseline characteristics of 1096 subjects, stratified by quartiles of fibrinogen.

Characteristics	Quartiles of fibrinogen (g/L)				value
	Q1 (≤3.01)	Q2 (3.02-3.65)	Q3 (3.66-4.55)	Q4 (≥4.56)
PAD no. (%)	188 (68.1%)	224 (81.8%)	234 (85.4%)	241 (88.6%)	<0.001
Male no. (%)	125 (45.3%)	125 (45.6%)	112 (40.9%)	112 (41.2%)	0.533
Age	63.60 ± 10.79	62.81 ± 11.44	62.80 ± 11.17	63.70 ± 11.46	0.668
Smoking (%)	89 (32.2%)	72 (26.3%)	101 (36.9%)	87 (32%)	0.068
Alcohol use (%)	67 (24.3%)	57 (20.8%)	60 (21.9%)	67 (24.6%)	0.661
Diabetes duration (months)	117.64 ± 85.96	107.87 ± 74.67	113.32 ± 87.46	112.98 ± 81.46	0.587
Stroke (%)	105 (38.0%)	110 (40.1%)	107 (39.1%)	112 (41.2%)	0.890
Hypertension (%)	142 (51.4%)	166 (60.6%)	194 (70.8%)	188 (69.1%)	<0.001
Weight (kg)	64.14 ± 11.22	64.63 ± 11.59	65.13 ± 11.36	64.15 ± 11.15	0.700
Height (cm)	161.53 ± 8.42	161.92 ± 8.55	162.5 ± 8.76	162.14 ± 7.98	0.587
BMI (kg/m^2)	24.49 ± 3.32	24.51 ± 3.73	24.63 ± 3.50	24.29 ± 3.34	0.711
Waist circumference (cm)	90.33 ± 10.53	90.52 ± 10.93	90.63 ± 10.91	90.07 ± 10.61	0.936
Hip circumference (cm)	94.93 ± 8.42	95.06 ± 8.61	95.41 ± 8.58	95.06 ± 10.79	0.938
Waist/hip ratio	0.95 ± 0.07	0.95 ± 0.07	0.95 ± 0.07	0.98 ± 0.51	0.619
TC (mmol/L)	4.67 ± 1.15	4.74 ± 1.34	4.69 ± 1.21	4.65 ± 2.54	0.926
TG (mmol/L)	1.82 ± 1.54	2.03 ± 1.90	1.76 ± 1.11	1.63 ± 1.28	0.021
HDL-C (mmol/L)	1.13 ± 0.32	1.09 ± 0.32	1.10 ± 0.32	0.97 ± 0.29	<0.001
LDL-C (mmol/L)	2.70 ± 0.87	2.70 ± 1.01	2.74 ± 0.94	2.72 ± 1.19	0.975
HbA1c (%)	9.08 ± 2.17	9.14 ± 2.20	9.14 ± 2.27	9.40 ± 2.24	0.340

PAD: peripheral arterial disease; BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol.