Peripheral Arterial Disease in Type 2 Diabetes Is Associated with an Increase in Fibrinogen Levels

Table 3

Univariate and multivariate analysis of risk factors for PAD.

	Univariate analysis		Multivariate analysis
	OR (95% CI)	value	OR (95% CI)	value
Sex	1.034 (0.763-1.402)	0.829	1.032 (0.749-1.422)	0.847
Age (year)	1.007 (0.994-1.021)	0.294	1.007 (0.993-1.021)	0.336
Smoking	1.134 (0.817-1.575)	0.453
Alcohol use	0.820 (0.579-1.160)	0.262
Diabetes duration (months)	1.000 (0.998-1.001)	0.612
Stroke	1.155 (0.846-1.577)	0.365
Hypertension	2.697 (1.983-3.668)	<0.001	2.434 (1.774-3.340)	<0.001
Weight (kg)	0.988 (0.975-1.001)	0.073
Height (cm)	0.996 (0.979-1.014)	0.676
BMI (kg/m^2)	0.959 (0.919-1.001)	0.053
Waist circumference (cm)	0.984 (0.971-0.998)	0.027	0.982 (0.968-0.997)	0.016
Hip circumference (cm)	0.985 (0.969-1.001)	0.072
Waist/hip ratio	1.053 (0.542-2.046)	0.879
Fibrinogen (g/L)	1.443 (1.250-1.665)	<0.001	1.332 (1.151-1.540)	<0.001
TC (mmol/L)	0.939 (0.865-1.020)	0.139
TG (mmol/L)	1.005 (0.907-1.113)	0.928
HDL-C (mmol/L)	0.419 (0.270-0.651)	<0.001	0.510 (0.321-0.811)	0.004
LDL-C (mmol/L)	1.001 (0.862-1.163)	0.986
HbA1c (%)	0.948 (0.887-1.013)	0.114

PAD: peripheral arterial disease; BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol.