Review Article
Noncoding RNAs Carried by Extracellular Vesicles in Endocrine Diseases
Table 2
Most relevant EV-miRNAs for biomarker application in endocrine diseases.
| | miRNA | Change | Source | Disease | Reference |
| | miR-23b | ↑ | Adipocyte-derived EVs | Obesity | Metabolic syndrome | [107] | | miR-122 | ↑ | Circulating EVs | NAFLD | Metabolic syndrome | [125] | | miR-130a | ↑ | Urinary EVs | Diabetic nephropathy | Metabolic syndrome | [152] | | ↓ | Circulating EVs | Coronary atherosclerosis | Metabolic syndrome | [169] | | miR-141 | ↓ | STB-derived EVs | Preeclampsia | [215] | | miR-145 | ↑ | Urinary EVs | Diabetic nephropathy | Metabolic syndrome | [152] | | miR-146a | ↑ | Circulating EVs | AITD | Thyroid disorders | [178] | | miR-148b | ↓ | Adipocyte-derived EVs | Obesity | Metabolic syndrome | [107] | | miR-155 | ↓ | Urinary EVs | Diabetic nephropathy | Metabolic syndrome | [152] | | ↑ | Circulating EVs | AITD | Thyroid disorders | [178] | | miR-192 | ↑ | Circulating EVs | NAFLD | Metabolic syndrome | [125] | | miR-424 | ↓ | Urinary EVs | Diabetic nephropathy | Metabolic syndrome | [152] | | miR-486-1-5p | ↑ | Circulating EVs | Preeclampsia | [216] | | miR-486-2-5p | ↑ | Circulating EVs | Preeclampsia | [216] | | miR-517a | ↓ | STB-derived EVs | Preeclampsia | [215] | | miR-517b | ↓ | STB-derived EVs | Preeclampsia | [215] | | miR-4269 | ↓ | Adipocyte-derived EVs | Obesity | Metabolic syndrome | [107] | | miR-4429 | ↑ | Adipocyte-derived EVs | Obesity | Metabolic syndrome | [107] |
|
|
EV: extracellular vesicle; NAFLD: nonalcoholic fatty liver disease; STB: syncytiotrophoblast; AITD: autoimmune thyroid disease. miRNA expression change: ↑: increased expression; ↓: reduced expression.
|
