Table of Contents Author Guidelines Submit a Manuscript
International Journal of Endocrinology
Volume 2018, Article ID 4537214, 6 pages
https://doi.org/10.1155/2018/4537214
Research Article

Vesicle-Associated Membrane Protein-Associated Protein A Is Involved in Androgen Receptor Trafficking in Mouse Sertoli Cells

Department of Urology, The People’s Hospital of Longhua, Shenzhen, China

Correspondence should be addressed to Hui Liang; moc.361@6791iuhgnail

Received 10 November 2017; Revised 18 January 2018; Accepted 5 February 2018; Published 4 March 2018

Academic Editor: Rosaria Meccariello

Copyright © 2018 Qiong Deng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. Chang, Y. T. Chen, S. D. Yeh et al., “Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 18, pp. 6876–6881, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. K. De Gendt, J. V. Swinnen, P. T. K. Saunders et al., “A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 5, pp. 1327–1332, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. R.-S. Wang, S. Yeh, L.-M. Chen et al., “Androgen receptor in sertoli cell is essential for germ cell nursery and junctional complex formation in mouse testes,” Endocrinology, vol. 147, no. 12, pp. 5624–5633, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Y. Tsai, S. D. Yeh, R. S. Wang et al., “Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 50, pp. 18975–18980, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. Q. Deng, Y. Wu, Z. Zhang et al., “Androgen receptor localizes to plasma membrane by binding to caveolin-1 in mouse Sertoli cells,” International Journal of Endocrinology, vol. 2017, Article ID 3985916, 8 pages, 2017. View at Publisher · View at Google Scholar · View at Scopus
  6. Q. Deng, Z. Zhang, Y. Wu et al., “Non-genomic action of androgens is mediated by rapid phosphorylation and regulation of androgen receptor trafficking,” Cellular Physiology and Biochemistry, vol. 43, no. 1, pp. 223–236, 2017. View at Publisher · View at Google Scholar · View at Scopus
  7. Q. Deng, D. Riquelme, L. Trinh et al., “Rapid glucocorticoid feedback inhibition of ACTH secretion involves ligand-dependent membrane association of glucocorticoid receptors,” Endocrinology, vol. 156, no. 9, pp. 3215–3227, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. J. P. Wyles, C. R. McMaster, and N. D. Ridgway, “Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum,” Journal of Biological Chemistry, vol. 277, no. 33, pp. 29908–29918, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. L. B. Smith and W. H. Walker, “The regulation of spermatogenesis by androgens,” Seminars in Cell & Developmental Biology, vol. 30, pp. 2–13, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. W. H. Walker, “Non-classical actions of testosterone and spermatogenesis,” Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 365, no. 1546, pp. 1557–1569, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. Nishimura, M. Hayashi, H. Inada, and T. Tanaka, “Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins,” Biochemical and Biophysical Research Communications, vol. 254, no. 1, pp. 21–26, 1999. View at Publisher · View at Google Scholar · View at Scopus
  12. M. L. Weir, A. Klip, and W. S. Trimble, “Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP,” Biochemical Journal, vol. 333, no. 2, pp. 247–251, 1998. View at Publisher · View at Google Scholar · View at Scopus
  13. L. A. Lapierre, P. L. Tuma, J. Navarre, J. R. Goldenring, and J. M. Anderson, “VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction,” Journal of Cell Science, vol. 112, pp. 3723–3732, 1999. View at Google Scholar
  14. A. Matsuda, Y. Suzuki, G. Honda et al., “Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways,” Oncogene, vol. 22, no. 21, pp. 3307–3318, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Sengupta, K. K. Miller, K. Homma et al., “Interaction between the motor protein prestin and the transporter protein VAPA,” Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol. 1803, no. 7, pp. 796–804, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Kawano, K. Kumagai, M. Nishijima, and K. Hanada, “Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT,” Journal of Biological Chemistry, vol. 281, no. 40, pp. 30279–30288, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. R. Dong, Y. Saheki, S. Swarup, L. Lucast, J. W. Harper, and P. De Camilli, “Endosome-ER contacts control actin nucleation and retromer function through VAP-dependent regulation of PI4P,” Cell, vol. 166, no. 2, pp. 408–423, 2016. View at Publisher · View at Google Scholar · View at Scopus