Uncoupling Protein 2 and Peroxisome Proliferator-Activated Receptor γ Gene Polymorphisms in Association with Diabetes Susceptibility in Chinese Han Population with Variant Glucose Tolerance
Table 12
Association of genotype with inflammation in UCP2.
Genotype
TNF-α (fmol/ml)
IL-6 (pg/ml)
rs660339
GG
23.44 ± 0.86
1.62 ± 0.08
AA
22.25 ± 0.95
1.42 ± 0.10
GA
22.40 ± 0.57
1.70 ± 0.05
value
0.527
0.034
rs659366
CC
23.31 ± 0.87
1.64 ± 0.08
TT
22.10 ± 0.94
1.46 ± 0.10
TC
22.55 ± 0.57
1.67 ± 0.05
value
0.598
0.111
rs649446
CC
23.28 ± 0.66
1.68 ± 0.06
TT
20.97 ± 1.48
1.95 ± 0.16
TC
22.37 ± 0.59
1.65 ± 0.06
value
0.257
0.001
rs7109266
GG
23.22 ± 0.66
1.68 ± 0.06
AA
20.78 ± 1.50
1.52 ± 0.17
GA
22.45 ± 0.60
1.65 ± 0.06
value
0.257
0.063
rs591758
GG
23.37 ± 0.86
1.64 ± 0.08
CC
21.81 ± 0.89
1.46 ± 0.10
CG
22.65 ± 0.59
1.68 ± 0.06
value
0.439
0.111
rs586773
AA
23.37 ± 0.86
1.64 ± 0.08
TT
21.81 ± 0.89
1.46 ± 0.10
AT
22.61 ± 0.59
1.67 ± 0.06
value
0.437
0.12
rs34408426
AA
23.37 ± 0.86
1.64 ± 0.08
GG
21.81 ± 0.89
1.46 ± 0.10
AG
22.56 ± 0.59
1.67 ± 0.06
value
0.434
0.124
rs3019463
CC
23.34 ± 0.86
1.64 ± 0.08
TT
22.15 ± 0.89
1.47 ± 0.10
TC
22.58 ± 0.60
1.66 ± 0.06
value
0.606
0.17
and . TNF-α: tumor necrosis factor-α; IL-6: interleukine-6. IL-6 has been nature logarithm transformed.
