Vanadyl Sulfate Effects on Systemic Profiles of Metabolic Syndrome in Old Rats with Fructose-Induced Obesity

Figure 1

Vanadyl sulfate (VS) effect on body mass of old obese male Wistar rats. Obesity was induced in rats with high-fructose diet (HFD) during 28 weeks, using a set of normal diet (ND) rats as comparative groups; stability in weight was observed during the next 4 weeks. After that, insulin sensitizer treatment (metformin (MET) or VS) was applied from week 32 to week 40, using saline solution (SS) as a control. (a) Body mass evolution after treatment with ND or HFD, and insulin sensitizers (starting week 32). comparing the HFD + VS group versus HFD plus MET or SS. (b) Body mass index (BMI) in animals after 28 weeks on ND or HFD (pretreatment bars), animals with a week of insulin sensitizer treatment (initial treatment bars), and animals with 8 weeks of insulin sensitizer treatment (posttreatment bars). comparing pretreatment versus initial treatment or posttreatment. (c) Abdominal fat tissue/body weight ratio in old obese male Wistar rats after 8 weeks with insulin sensitizer treatment. comparing the HFD + VS group versus HFD plus MET or SS. Data are ().

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