Vanadyl Sulfate Effects on Systemic Profiles of Metabolic Syndrome in Old Rats with Fructose-Induced Obesity

Figure 5

Effect of VS on lipid plasma levels in old obese male Wistar rats. After obesity induced with high-fructose diet (HFD) during 28 weeks, insulin sensitizer treatment (metformin (MET) or VS) was applied from week 32 to week 40, using saline solution (SS) as a control. (a) Triglyceride fasting plasma levels in rats after 32 weeks on ND or HFD (pretreatment bars) and after 8 weeks of insulin sensitizer treatment (posttreatment bars). HFD + SS post-treatment. comparing HFD + VS post-treatment versus HFD + SS or HFD + MET post-treatment. (b, c) HDL and LDL cholesterol plasma levels in rats after 32 weeks on ND or HFD (pretreatment bars) and after 8 weeks of insulin sensitizer treatment (posttreatment bars) (nonsignificant differences were found). (d) Triglyceride/HDL ratio in rats after 32 weeks on ND or HFD (pretreatment bars) and after 8 weeks of insulin sensitizer treatment (posttreatment bars). comparing HFD + VS post-treatment versus HFD + SS or HFD + MET post-treatment. Data are ().

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