Cardiometabolic Changes in Different Gonadal Female States Caused by Mild Hyperuricemia and Exposure to a High-Fructose Diet
Table 5
Lipid profile. Comparative effect of the gonadal state at different stages of treatments.
NGN
HGN
Total cholesterol (mg/dl)
Control
53.15 ± 2.13
76.84 ± 2.40
<0.0001
Fructose
56.68 ± 2.13
72.16 ± 4.66
0.01
OA
58.77 ± 1.66
73.61 ± 2.25
0.0003
FOA
54.93 ± 2.22
91.96 ± 4.38#
<0.0001
Triglyceride (mg/dl)
Control
50.13 ± 4.77
61.48 ± 10.28
NS
Fructose
73.27 ± 12.72
83.98 ± 6.06
NS
OA
57.50 ± 9.8
57.61 ± 7.53
NS
FOA
83.58 ± 17.36
101.20 ± 11.68&
NS
HDL (mg/dl)
Control
36.49 ± 4.43
36 ± 1.03
NS
Fructose
33.77 ± 1.76
34.39 ± 1.08
NS
OA
31.69 ± 1.39
33.14 ± 0.70
NS
FOA
32.72 ± 1.77
33.67 ± 1.11
NS
No HDL (mg/dl)
Control
20.33 ± 1.65
32.60 ± 1.66
0.0006
Fructose
22.93 ± 2.58
34.77 ± 1.88
0.003
OA
27.01 ± 1.61
39.14 ± 3.78
0.01
FOA
23.61 ± 1.84
46.67 ± 2.18†∧
<0.0001
TG/HDL
Control
1.56 ± 0.21
1.41 ± 0.21
NS
Fructose
2.18 ± 0.34
2.04 ± 0.25
NS
OA
1.84 ± 0.35
1.37 ± 0.16
NS
FOA
2.45 ± 0.42
2.33 ± 0.19
NS
Data are expressed as mean ± SEM. NGN: normogonadic; HNG: hypogonadic; OA: oxonic acid; FOA: fructose and oxonic acid; NS: nonsignificant. HGN fructose versus HGN FOA group. HGN OA versus HGN FOA group. HGN control versus HGN FOA group. HNG OA versus HGN FOA group. HNG control versus HGN FOA group. HGN fructose versus HGN FOA group. HGN control versus HGN FOA group.
