Leptin Modifies the Rat Heart Performance Associated with Mitochondrial Dysfunction Independently of Its Prohypertrophic Effects

Figure 6

Leptin induces overexpression of the protein c-ACT and increases phosphorylation of STAT3. (a) The c-ACT protein content was measured by Western blotting of the heart homogenate using GAPDH as the loading control. Bars represent the of four independent mitochondrial preparations. (b) The phosphorylated STAT3 protein content was measured by Western blotting of the heart homogenate using total STAT3 as a reference control. (c) The STAT3 protein content was measured by Western blotting of the heart homogenate using GAPDH as the loading control. The values indicate the , ; versus the control group.