Research Article

Comparison of Initial Clinical Presentations between Primary Hyperparathyroidism Patients from New Brunswick and Changsha

Table 1

Comparison of clinical features of PHPT patients in New Brunswick and Changsha from 2010 to 2016.

Clinical featuresChangshaNew Brunswick value
Normal rangeNormal range

Age (years)52.4 ± 15.458.4 ± 12.5<0.01
Female (% )66% (87/131)77% (130/169)<0.05
Duration (years)5.8 ± 7.74.4 ± 6.40.7
BMI (kg/m2)21.5 ± 3.929.3 ± 6.5<0.001
Ca (mg/dL)13.1 ± 2.38.4–10.111.1 ± 0.68.6–10.4<0.001
Serum PTH (pg/mL)676.4 ± 564.714.0–63.0138.7 ± 99.715.0–65.0<0.001
25 (OH) D (ng/mL)14.2 ± 8.130.0–100.029.5 ± 11.030.0–80.0<0.001
Albumin (g/dL)3.9 ± 0.64.0–5.54.3 ± 0.53.5–5.5<0.001
Corrected Ca (mg/dL)13.2 ± 2.510.8 ± 0.7<0.001
AKP (U/L)383.7 ± 645.950.0–135.086.0 ± 30.445.0–115.0<0.001
Glucose (mg/dL)92.7 ± 23.270.0–110.099.7 ± 19.665.0–99.0<0.001
Creatinine (mg/dL)1.1 ± 0.70.5–1.50.9 ± 0.30.5–1.20.7
Kidney stone (%)62% (81/131)31% (52/169)<0.001
Adenoma (%)92% (85/92)48% (77/159)<0.001

PTH: parathyroid hormone; BMI: body mass index; Ca: serum calcium; 25 (OH) D: 25-hydroxyvitamin D; AKP: alkaline phosphatase.