Adult Height after Growth Hormone Treatment at Pubertal Onset in Short Adolescents Born Small for Gestational Age: Results from a Belgian Registry-Based Study
Table 3
Comparison of auxological data at onset of puberty and during puberty between the PrePUB and PUB groups.
n
PrePUB group
PUB group
Significance
n
Males ()
Females ()
n
Males ()
Females ()
Height gain from start of GH until pubertal onset
Delta height, SDS
53
26
0.9 ± 0.6
27
0.2 ± 0.2
Data at start of puberty
Age (yr)
68
26
13.4 ± 1.3
12.1 ± 2.0
42
13.4 ± 1.1
11.6 ± 1.2
/
Height, SDS
68
26
−2.3 ± 0.6
42
−3.1 ± 0.7
Weight, SDS
68
26
−2.2 ± 1.0
42
−2.7 ± 1.1
BMI, SDS
68
26
−1.0 ± 0.9
42
−1.2 ± 1.2
Height gain from onset of puberty until AH
Delta height, SDS
68
26
0.2 ± 0.9
42
0.6 ± 0.7
Delta height (cm)
68
26
23.2 ± 3.3
16.7 ± 5.3
42
28.2 ± 5.3
21.5 ± 5.6
/
In males from the PrePUB group versus the PUB group/in females from the PrePUB group versus the PUB group. In the PUB group, height gain from start of GH until pubertal onset was calculated only if GH therapy was started before or at onset of puberty.
