Research Article
Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma
Table 1
Clinicopathologic characteristic of female and male PTC patients.
| | Male () | Female () | value |
| | Age at diagnosis, M (range) | 41 (9–78) | 43 (12–84) | 0.265 | | Age (<45 y/≥45 y) | 92/60
60.5%/39.5% | 244/194
55.7%/44.3% | 0.301 | | Hashimoto’s thyroiditis, n (%) | 14 (9.27%) | 87 (19.86%) | 0.003 | | TSH, μIU/mL, M (range) | 1.63 (0.07–8.27) | 2.02 (0.07–72.8) | 0.017 | | T4, μg/dL, M (range) | 7.97 (4.21–13.2) | 7.95 (2–25.9) | 0.642 | | T3, ng/mL, M (range) | 1.43 (0.52–2.55) | 1.33 (0.5–4.57) | 0.098 | | TGAB, %, M (range) | 3.76 (2.45–53.6) | 4.55 (1.82–63.7) | <0.001 | | TMAB, %, M (range) | 3.08 (1.69–39.8) | 3.54 (1.43–44) | 0.001 | | Ultrasonographic characteristics of suspicious nodules | | | | | Tumor size (≦1 cm/>1 cm) | 35/117
23%/77% | 104/334
23.7%/76.3% | 0.488 | | Multifocal/unifocal | 64/88
42.1%/57.9% | 195/243
44.5%/55.5% | 0.754 | | Bilateral/unilateral | 42/110
27.6%/72.4% | 134/304
30.6%/69.4% | 0.515 | | Margin (regular/irregular) | 60/84
41.7%/58.3% | 179/228
44%/56% | 0.721 | | Border (clear/obscure) | 75/71
51.4%/48.6% | 214/207
50.8%/49.2% | 0.911 | | Hypoechoic/Hyper- or isoechoic calcification | 139/10
93.3%/6.7% | 418/20
95.4%/4.6% | 0.313 | | Non-/micro-/coarse calcification | 27/105/20
17.8%/69.1%/13.1% | 93/277/66
21.3%/63.5%/15.1% | 0.483 | Vascularization
None/low/middle/high | 1/42/37/33
0.8%/37.2%/32.7%/29.2% | 25/132/118/55
7.6%/40%/35.8%/16.7% | 0.004 | | Central lymph node metastasis | | | | | CLNM, n (%) | 108 (71.05%) | 238 (54.33%) | <0.001 | | Number of removed CLNs, M (range) | 5 (0–27) | 6 (0–41) | 0.139 | | Number of metastatic CLNS, M (range) | 2 (0–20) | 1 (0–19) | <0.001 |
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US: ultrasonography; CLNM: central lymph node metastases; NCLNM: central lymph node metastases negative; PTC: papillary thyroid cancer.
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