Research Article
Gender-Specific Risk of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma
Table 2
Univariate analysis of the correlation between clinical factors of the primary tumor and rate of CLNM in PTC patients.
| | CLNM () | NCLNM () | |
| | Gender (male/female) | 108/238
31.2%/68.8% | 44/200
18%/82% | <0.001 | | Age at diagnosis, M (range) | 38 (9–79) | 48 (13–84) | <0.001 | | Age (<45 y/≥45 y) | 239/107
69.1%/30.9% | 97/147
39.8%/60.2% | <0.001 | | Hashimoto’s thyroiditis, present/absent | 53/293
15.3%/84.7% | 48/196
19.7%/80.3% | 0.172 | | TSH, μIU/mL, M (range) | 1.99 (0.07–26.5) | 1.79 (0.07–28.3) | 0.676 | | T4, μg/dL, M (range) | 7.97 (4.36–24.4) | 7.92 (3.3–15.1) | 0.293 | | T3, ng/mL, M (range) | 1.35 (0.5–2.55) | 1.35 (0.63–2.28) | 0.415 | | TGAB, %, M (range) | 4.3 (1.98–62.6) | 4.27 (1.82–63.7) | 0.671 | | TMAB, %, M (range) | 3.48 (1.53–41.7) | 3.32 (1.69–44) | 0.489 | | Ultrasonographic characteristics of suspicious nodules | | Tumor size (≦1 cm/>1 cm) | 60/286
17.3%/82.7% | 79/165
32.4%/67.6% | <0.001 | | Multifocal/unifocal | 167/179
48.3%/51.7% | 92/152
37.7%/62.3% | 0.005 | | Bilateral/unilateral | 110/236
31.8%/68.2% | 66/178
27%/73% | 0.235 | | Margin (regular/irregular) | 129/194
39.9%/60.1% | 110/118
48.2%/51.8% | 0.042 | | Border (clear/obscure) | 163/168
49.2%/50.8% | 126/108
53.8%/46.2% | 0.330 | | Hypoechoic/Hyper or isoechoic calcification | 325/19
94.5%/5.5% | 232/11
95.5%/4.5% | 0.670 | | Non-/micro-/coarse calcification | 53/243/48
15.4%/70.6%/14% | 66/140/38
27%/57.4%/15.6% | 0.001 | Vascularization
None/low/middle/high | 12/99/87/59
4.7%/38.5%/33.8%/23% | 14/75/68/29
7.5%/40.3%/36.6%/15.6% | 0.661 |
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CLNM: central lymph node metastases; NCLNM: central lymph node metastases negative; PTC: papillary thyroid cancer.
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