Thyroid Function in Korean Adolescents with Obesity: Results from the Korea National Health and Nutrition Examination Survey VI (2013–2015)
Table 1
Characteristic and laboratory data according to obesity, sex, and age in 10–19-year-old Korean adolescents.
Normal
Overweight
Obesity
for trend
N (%)
851 (80.7%)
103 (8.7%)
113 (10.6%)
—
Estimated number of subjects
2,113,591
228,910
276,292
—
Sex (male, %)
443 (51.0%)
57 (53.7%)
59 (53.0%)
0.859
Age (yr)
15.2 ± 0.1
14.5 ± 0.3
14.9 ± 0.2
0.468
BMI (kg/m2)
20.2 ± 0.1
24.5 ± 0.1
28.7 ± 0.3
<0.001
BMI z-score
−0.29 ± 0.03
1.32 ± 0.02
2.54 ± 0.08
<0.001
WC (cm)
69.0 ± 0.3
79.1 ± 0.6
88.4 ± 1.1
<0.001
WHR (%)
42.5 ± 0.2
48.3 ± 0.3
53.5 ± 0.5
<0.001
Systolic BP (mmHg)
107.8 ± 0.4
112.6 ± 1.1
115.6 ± 1.0
<0.001
Diastolic BP (mmHg)
66.7 ± 0.3
67.4 ± 1.1
68.0 ± 0.8
0.133
Fasting glucose (mg/dL)
90.7 ± 0.3
91.7 ± 0.7
94.8 ± 2.5
0.081
HbA1c (%)
5.40 ± 0.01
5.45 ± 0.04
5.59 ± 0.11
0.064
Total cholesterol (mg/dL)
156.9 ± 0.9
159.2 ± 3.3
165.5 ± 2.8
0.004
HDL-C (mg/dL)
52.2 ± 0.4
49.2 ± 1.1
45.0 ± 0.9
<0.001
Triglyceride (mg/dL)
72.4 ± 1.3
84.4 ± 5.1
90.6 ± 4.6
<0.001
AST (IU/L)
18.4 ± 0.3
18.8 ± 0.9
19.9 ± 0.6
0.043
ALT (IU/L)
14.0 ± 0.5
17.5 ± 2.1
23.7 ± 1.5
<0.001
Free T4 (ng/mL)
1.30 ± 0.01
1.26 ± 0.02
1.25 ± 0.02
0.001
TSH (mIU/L)
2.73 ± 0.06
2.77 ± 0.02
3.24 ± 0.22
0.031
Subclinical hyperthyrotropinemia, n (%)
54 (5.8%)
6 (4.9%)
11 (10.0%)
0.221
Abdominal obesity, n (%)
17 (2.3%)
19 (19.4%)
86 (77.6%)
<0.001
Hypertension, n (%)
24 (2.4%)
6 (9.2%)
12 (10.6%)
<0.001
Hyperglycemia, n (%)
74 (8.4%)
13 (10.6%)
14 (13.3%)
0.250
Hypertriglyceridemia, n (%)
47 (5.5%)
18 (15.8%)
19 (16.2%)
<0.001
Hypo-HDL-C, n (%)
96 (12.1%)
16 (14.0%)
31 (26.3%)
<0.001
Metabolic syndrome, n (%)
4 (0.4%)
2 (1.9%)
15 (13.9%)
<0.001
Data are presented as weighted mean ± standard error or frequency (weighted percentage). TC, HDL-C, and TG were log-transformed for analysis and expressed as geometric mean ± standard error. BMI: body mass index; WC: waist circumference; WHR: waist-height ratio; BP: blood pressure; HDL-C: high-density lipoprotein cholesterol; AST: aspartate transaminase; ALT: alanine transaminase; TSH: thyroid-stimulating hormone.
