Research Article
The Influence of Obesity on Puberty and Insulin Resistance in Mexican Children
Table 1
Characteristics of study participants.
| | Characteristic | Group | value | | General () | Children with obesity () | Normal weight () |
| | Gender | | | | | | Female, n (%) | 189 (50) | 88 (47.6) | 101 (52.3) | 0.41 | | Male, n (%) | 189 (50) | 97 (52.4) | 92 (47.7) | | Birth weight (g) | 3099.6 ± 623.7 | 3131.4 ± 6 | 3069.9 ± 633.1 | 0.827 | | Weight (kg) | 52.6 ± 17.7 | 64.2 ± 16.0 | 41.4 ± 10.6 | <0.001 | | Height (m) | 1.5 ± 0.1 | 1.56 ± 0.13 | 1.5 ± 0.14 | <0.001 | | Waist circumference (cm) | 79.0 ± 14.4 | 89.8 ± 11.4 | 68.6 ± 7.8 | <0.001 | | Body mass index (kg/m2) | 22.1 ± 4.9 | 26.2 ± 3.6 | 18.2 ± 2.0 | <0.001 | | Diastolic blood pressure (mmHg) | 76.3 ± 11.6 | 76.4 ± 11.7 | 76.2 ± 11.5 | 0.966 | | Systolic blood pressure (mmHg) | 108.5 ± 11.4 | 110.9 ± 11.0 | 106.1 ± 11.3 | <0.001 | | Family history of DM2, n (%) | 282 (74.6) | 134 (72.4) | 148 (76.4) | 0.406 | | Acanthosis nigricans, n (%) | 195 (51.6) | 159 (85.9) | 36 (18.7) | <0.001 | | Tanner stage | | | | | | 1 | 72 (19.0) | 35 (18.9) | 37 (19.2) | 0.662 | | 2 | 73 (19.3) | 41 (22.2) | 32 (16.6) | | 3 | 81 (21.4) | 37 (20.0) | 44 (22.8) | | 4 | 80 (21.2) | 36 (19.5) | 44 (22.8) | | 5 | 72 (19.0) | 36 (19.5) | 36 (18.7) | | Fasting glucose (mg/dl) | 79.6 ± 8.4 | 81.1 ± 8.6 | 78.2 ± 7.9 | 0.001 | | Fasting insulin (μIU/mL) | 11.7 ± 9.2 | 15.9 ± 10.6 | 7.6 ± 4.9 | <0.001 | | HOMA-IR | 2.3 ± 1.9 | 3.23 ± 2.19 | 1.5 ± 1.1 | <0.001 | | HOMA-IR > 3.16, n (%) | 87 (23.0) | 74 (40.0) | 13 (6.7) | <0.001 |
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HOMA-IR cutoff value for pediatric population. |
