Characterization of In Vivo Retinal Lesions of Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy

Figure 1

(a) Example of an arteriole in confocal and multiply scattered light (MSL) and (b) AOSLO imaging. Finer details of the vessel walls are visualized with MSL AOSLO imaging, which increases the sensitivity to scattered light reflected from vasculature and erythrocytes. (c–f) Intraretinal microvascular abnormalities (IRMA). (g, h) Neovascular proliferations (NVE) growing anteriorly to the RNFL. Arrowheads indicate feeder/draining vessels. In (d), the AOSLO image is focused at the photoreceptor level and displays a regular photoreceptor mosaic surrounding the blurred shadow of an IRMA. In (g) and (h), the 3-dimensional structure of the NVE results in clear focus on some vascular loops and blurry vessel formations in other areas of the NVE.

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