Hypophyseal Involvement in Immunoglobulin G4-Related Disease: A Retrospective Study from a Single Tertiary Center

Table 3

Evaluation of pituitary function before treatment started.

Patient ID	1	2	3	4	5	6	7	8	9	10
IGF1 (age-adjusted normal range) (ng/ml)	160 (75–212)	79 (75–212)	143 (81–225)	124 (87–238)	74 (94–252)	239 (101–267)	74 (109–284)	90 (81–225)	147 (226–903)	197 (94–252)
Total testosterone (male) (ng/ml)/estradiol (female) (pg/ml)	0.85	0	0	1.56	1.33	4.55	2.91	10.3	2.86	<0.1
FSH/LH (IU/l)	12.82/6.87	0.48/0.12	0.8/0	10.79/6.53	<0.2/<0.2	9.16/4.45	6.09/3.80	47.6/21/87	0.56/1.1	0.78/0.26
Free T4 (ng/dl)	1.63	0.87	0.85	2.137	0.482	1.099	1.273	1.033	Normal	0.464
TSH (μIU/ml)	1.216	0.186	1.534	0.199	1.45	3.087	1.238	2.064	Normal	4.668
Morning serum cortisol (μg/dl)	0.54	1.44	Normal	10.6	13.76	29.1	11.46	14.41	<1	7.98
Morning serum ACTH (pg/ml)	Normal	7	Normal	31	22.5	44	11.6	57.4	1.34	14.9
24 h urine volume (l)	4	8	4	4.5	10	3.5	Normal	5	6	Normal
Postdehydration plasma/urine osmolality (mOsm/kg H2O)	287/301	151/321	267/307	n/d	n/d	n/d	n/a	n/d	167/300	n/a
Desmopressin trial	+	+	+	+	+	+	n/a	+	+	n/a