Research Article
Hypophyseal Involvement in Immunoglobulin G4-Related Disease: A Retrospective Study from a Single Tertiary Center
Table 5
Clinical features of this study and a previous review.
| | This study | Shikuma et al. [13] |
| | Mean age of onset (years) | 46.1 ± 13.1 | 64.2 ± 13.9 | | Extrapituitary lesions | | | | Retroperitoneal fibrosis | 20% | 26.2% | | Mikulicz’s disease, Küttner’s tumor | 70% | 25.0% | | Lymph node swelling | 50% | 23.8% | | Lung inflammatory pseudotumor interstitial pneumonia | 20% | 20.2% | | Autoimmune pancreatitis | 10% | 14.3% | | Tubulo-interstitial nephritis, kidney inflammatory pseudotumor | 20% | 11.9% | | Hypertrophic pachymeningitis | 0 | 8.3% | | Orbital pseudotumor iridocyclitis | 0 | 8.3% | | Liver inflammatory pseudotumor | 0 | 3.6% | | Nasal sinus inflammatory pseudotumor | 20% | 2.4% | | Sclerosing cholangitis | 0 | 2.4% | | Riedel’s thyroiditis | 20% | 1.2% | | Inflammatory aneurism | 10% | 1.2% | | Gastric wall thickness | 0 | 1.2% | | Iliopsoas muscle | 0 | 1.2% | | Prostatitis | 0 | 1.2% | | Pituitary hormone deficiency | | | | ADH | 80% | 72.0% | | FSH/LH | 50% | 48.8% | | ACTH | 30% | 47.6% | | TSH | 20% | 41.5% | | GH | 10% | 41.5% | | MRI features | | | | Thickened stalk alone | 70% | 21.4% | | Pituitary mass alone | 10% | 14.3% | | Both | 20% | 64.3% |
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