International Journal of Endocrinology / 2018 / Article / Tab 5

Research Article

Hypophyseal Involvement in Immunoglobulin G4-Related Disease: A Retrospective Study from a Single Tertiary Center

Table 5

Clinical features of this study and a previous review.

This studyShikuma et al. [13]

Mean age of onset (years)46.1 ± 13.164.2 ± 13.9
Extrapituitary lesions
 Retroperitoneal fibrosis20%26.2%
 Mikulicz’s disease, Küttner’s tumor70%25.0%
 Lymph node swelling50%23.8%
 Lung inflammatory pseudotumor interstitial pneumonia20%20.2%
 Autoimmune pancreatitis10%14.3%
 Tubulo-interstitial nephritis, kidney inflammatory pseudotumor20%11.9%
 Hypertrophic pachymeningitis08.3%
 Orbital pseudotumor iridocyclitis08.3%
 Liver inflammatory pseudotumor03.6%
 Nasal sinus inflammatory pseudotumor20%2.4%
 Sclerosing cholangitis02.4%
 Riedel’s thyroiditis20%1.2%
 Inflammatory aneurism10%1.2%
 Gastric wall thickness01.2%
 Iliopsoas muscle01.2%
 Prostatitis01.2%
Pituitary hormone deficiency
 ADH80%72.0%
 FSH/LH50%48.8%
 ACTH30%47.6%
 TSH20%41.5%
 GH10%41.5%
MRI features
 Thickened stalk alone70%21.4%
 Pituitary mass alone10%14.3%
 Both20%64.3%