Clinical Study

Fatty Liver as a Potential Surrogate for Waist Circumference in the Diagnosis of Metabolic Syndrome: A Population-Based Study among Chinese Adults

Table 1

Basic characteristics of the study population, grouped by WC and NAFLD.

Normal WCAbnormal WC
Without NAFLD (1)With NAFLD (2)Without NAFLD (3)With NAFLD (4)

Sex (women), n (%)3014 (58.4)273 (29.0)ab1358 (72.9)1057 (61.1)
Age, yrs51 (41, 61)52 (42, 60)b60 (51, 68)57 (49, 64)
Components of MetS
 WC, cm74 (69, 78)81 (77, 86)ab88 (83, 93)92 (86, 97)
 TG, mmol/L1.1 (0.83, 1.51)1.73 (1.2, 2.46)ab1.38 (1.02, 1.94)1.89 (1.4, 2.67)
 HDL, mmol/L1.47 (1.27, 1.69)1.3 (1.11, 1.49)a1.38 (1.18, 1.59)1.28 (1.12, 1.47)
 SBP, mmHg124 (112, 139)130 (118, 146)ab137 (123, 152)140 (126, 155)
 DBP, mmHg76 (68, 84)81 (73, 89)a81 (73, 89)85 (77, 93)
 FPG, mmol/L5.2 (4.86, 5.63)5.34 (4.92, 5.95)a5.37 (4.94, 5.96)5.59 (5.10, 6.46)
Insulin resistance
 Insulin, pmol/L28 (20.2, 38.8)35.75 (25.3, 50.95)a36.75 (26.5, 51)48 (35, 67.6)
 HOMA-IR0.95 (0.67, 1.32)1.29 (0.86, 1.79)a1.29 (0.91, 1.82)1.83 (1.25, 2.65)
 MetS z-score (4 factors)−2.44 (−3.67, −1.03)−0.80 (−2.06, 0.83)ab−0.88 (−2.27, 0.73)0.48 (−0.99, 2.39)
Measures of liver function
 AST, U/L22 (19, 27)24 (20, 30)a23 (20, 28)25 (21, 31)
 ALT, U/L16 (12, 22)22 (16, 32)ab17 (13, 23)23 (17, 34)
Living area, %
 Rural58.5041.10ab63.4059.10
 Urban41.5058.9036.6040.90
Occupational position, %
 Manual50.6037.10ab63.0054.20
 Nonmanual36.5047.7026.0033.10
 Self-employed12.9015.2011.0012.70
Current smoking status, %20.8031.40b16.2021.40

Data were shown as median (interquartile range) or percentages (%). WC: waist circumference; MetS z-score (4 factors) includes BG, TG, HDL, and BP z-scores; abdominal WC: WC ≥ 90 cm for males and WC ≥ 80 cm for females; normal WC: <90 cm for males and <80 cm for females. Data were analyzed by adjusting for age and sex. value of <0.05 normal WC with NAFLD (2) compared with normal WC without NAFLD (1). value of <0.05 normal WC with NAFLD (2) compared with abnormal WC without NAFLD (3).