Review Article

Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors

Table 1

The granin family and biological functions mediated by Cg A-derived peptides.

Granin proteinsCg A-derived peptidesCg A-peptide-mediated biologic function

Chromogranin A (Cg A)
Chromogranin B (CgB)
Secretogranin (Sg) II (CgC)
Sg III (1B1075)
Sg IV (HISL-19)
Sg V (7B2)
Sg VI (NESP55)
VGF (Sg VII)
proSAAS (SgVIII)
Vasostatin-1 (VST I: hCgA1–76)
Vasostatin-2 (VST II: hCgA1–115) Pancreastatin (PST: hCgA357–428)
Catestatin (CST: hCgA352–372)
Parastatin (PARA: pCgA347–419)
Regulation of glucose balance
Regulation of lipid metabolism
Regulation of cardiovascular system
Regulation of neurotrasmitter release
Regulation of the immune system
Regulation of parathormone secretion