Research Article
Sheehan’s Syndrome Revisited: Underlying Autoimmunity or Hypoperfusion?
Table 1
Demographic characteristics and clinical variables.
| | Characteristic | Total | Hypopituitarism | Normal test | value | | Patients, n (%) | | | |
| | Age (years), mean (SD) | 26.35 (±5.83) | 26.40 (±5.94) | 26.33 (±6.01) | 0.951 | | Menarche (years), mean (SD) | 11.9 (±1.20) | 12.40 (±1.14) | 11.73 (±1.22) | 0.298 | | Previous hemorrhage, n (%) | 1 (5) | 0 (0) | 1 (6.7) | 0.554 | | Gravida, n (%) | | 1 | 7 (35) | 0 (0) | 7 (46.7) | 0.077 | | 2 | 6 (30) | 3 (60) | 3 (20) | | | ≥3 | 7 (35) | 2 (40) | 5 (33.3) | | | Cesarean section, n (%) | 9 (45) | 1 (20) | 8 (53.3) | 0.319 | | Weeks of gestation, mean (SD) | 38.16 (±2.29) | 38.56 (±1.44) | 38.02 (±2.56) | 0.745 | | Hemorrhage etiology, n (%) | | Uterine atony | 13 (65) | 3 (60) | 10 (66.7) | 0.285 | | Preeclampsia/eclampsia | 1 (5) | 0 (0) | 1 (6.7) | | | Uterine rupture | 1 (5) | 1 (20) | 0 (0) | | | Placenta previa | 2 (10) | 1 (20) | 1 (6.7) | | | Vaginal tearing | 3 (15) | 0 (0) | 3 (20) | | | Hysterectomy, n (%) | 10 (50) | 4 (80) | 6 (40) | 0.303 | | Hemorrhage (ml), mean (SD) | 2070 (±1130.95) | 2420 (±1247.79) | 1953.33 (±1110.25) | 0.439 | | Infused solutions (ml) | 3363.15 (±1754.74) | 4290 (±2237.85) | 3032.14 (±1508) | 0.176 | | RBC units (500 ml each), mean (SD) | 3.4 (±2.7) | 4.6 (±3.3) | 3.1 (±2.5) | 0.284 | | Shock grade, n (%) | | 2 | 5 (25) | 0 (0) | 5 (33.3) | 0.157 | | 3 | 6 (30) | 3 (60) | 3 (20) | | | 4 | 9 (45) | 2 (40) | 7 (46.7) | | | Shock index, mean (SD) | 1.39 (±0.56) | 1.74 (±0.53) | 1.27 (±0.54) | 0.113 | | Systolic BP, mean (SD) | 94.9 (±24.79) | 77.6 (±17.28) | 100.66 (±24.63) | 0.07 | | Diastolic BP, mean (SD) | 58.1 (±18.00) | 54.4 (±20.16) | 59.33 (±17.81) | 0.825 | | Heart rate, mean (SD) | 120.65 (±20.60) | 128.2 (±12.49) | 118.13 (±22.45) | 0.358 | | Time to stability (minutes), mean (SD) | 74.21 (±28.34) | 88.75 (±38.16) | 70.33 (±25.38) | 0.26 | | Hb preevent, mean (SD) | 12.13 (±1.25) | 12.1 (±0.58) | 12.15 (±1.42) | 0.938 | | Post Hb, mean (SD) | 8.92 (±1.90) | 10 (±2.13) | 8.56 (±1.74) | 0.148 | | Delta Hb, mean (SD) | −3.217 (±2.10) | −2.1 (±2.12) | −3.58 (±2.02) | 0.119 |
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RBC: red blood cell; BP: blood pressure; Hb: hemoglobin.
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