Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members’ View in an <i>AIP</i> Mutation-Positive Family

<div>(a) Pituitary MRI of the proband’s second cousin (case 4) showing right 6 mm and left 4 mm PAs. (b) Immunostaining of the right (upper 2 panels) and left (lower 2 panels) PAs. The right adenoma shows strong GH and scattered prolactin staining. The lower panels show the left adenoma containing adenoma tissue (A), which stains strongly for prolactin and shows only scattered GH staining, and normal pituitary tissue (NP) which is visible in many GH-stained cells.</div>

International Journal of Endocrinology

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Figure 3: Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members’ View in an <i>AIP</i> Mutation-Positive Family 

Figure 3 | Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members’ View in an AIP Mutation-Positive Family 