Clinical, Genetics, and Bioinformatic Characterization of Mutations Affecting an Essential Region of PLS3 in Patients with BMND18

Figure 4

The RMSD is calculated on Cα atoms of the wild-type plastin-3 (red) and the mutant (Glu249_Ala250ins12) (blue) structure (a), respectively. (b) Atomic fluctuations (RMSF) is calculated from the Cα of the wild-type (red) and mutant (blue) plastin-3 during MD simulations.

(a)

(b)