Apelin in Reproductive Physiology and Pathology of Different Species: A Critical Review

<div>Apelin effect on ovarian physiology and pathology. eNOS: endothelium nitric oxide; Bcl-2: B-cell lymphoma 2; APJ: apelin receptor; Akt: protein kinase B; MAPK: mitogen-activated protein kinases; AMPK: 5<svg height="11.4859pt" id="M5" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -11.4361 3.89517 11.4859" width="3.89517pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M310 541L304 571C290 586 211 619 185 610L80 76L131 52L310 541Z" id="g50-31"></path></g></svg>AMP-activated kinase; PI3K: phosphoinositide 3-kinase; PCOS: polycystic ovary syndrome.</div>

International Journal of Endocrinology

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Figure 4

Figure 4: Apelin in Reproductive Physiology and Pathology of Different Species: A Critical Review 