Focusing on Sodium Glucose Cotransporter-2 and the Sympathetic Nervous System: Potential Impact in Diabetic Retinopathy

Figure 2

Sympathetic nervous system hyperactivation in the Schlager mouse is associated with neural damage of the outer layers of the retina. Haematoxylin and eosin staining of the eye of the Schlager mouse highlights that the outer plexiform, outer nuclear, and photoreceptor layers are all absent. 1: nerve fibre layer; 2: ganglion cell layer; 3: inner plexiform layer; 4: inner nuclear layer; 5: outer plexiform layer; 6: outer nuclear layer; 7: photoreceptor layer, and 8: choroid. Magnification: 200x.

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