Positive Association of Metabolic Syndrome with a Single Nucleotide Polymorphism of Syndecan-3 (rs2282440) in the Taiwanese Population

Table 3

Anthropometric and cardiometabolic measures according to SDC3 polymorphism (rs2282440) genotypes.

	C/C	C/T	T/T
	Age, yrs	39.2	37.2		38	0.2834
Sex (women), %	65.6	64.3	57.6	0.3324
BMI, kg/m^2	26.0	26.4	27.9	0.0132
WC, cm	82.8	83.5	87.4	0.039
PFM, %	31.9	32.3	34.0	0.0139
SBP, mmHg	122.5	123.9	127.2	0.14
DBP, mmHg	77.1	77.8	79.7	0.3282
TG, mg/dl	105.7	110.9	131.1	0.0407
HDL-C, mg/dl	57.4	56.1	52.2	0.0539
FPG, mg/dl	96.9	93.8	98.4	0.1857
HOMA-IR	2.6	2.9	3.3	0.2287
HOMA-IR group
≥ 75%tile, n (%)	39 (32.8)	80 (27.2)	53 (40.2)	0.0437
hs-CRP	0.21	0.21	0.21	0.1374
hs-CRP group
≥ 75%tile, n (%)	27 (22.7)	77 (26.2)	49 (37.1)	0.0205
Obesity, n (%)	68 (57.1)	162 (55.1)	96 (72.7)	0.0058

values were calculated by using the Proc CATMOD test for categorical variables after adjustment for sex and general linear models for continuous variables after adjustment for sex and age. BMI: body mass index; WC: waist circumference; PFM: percent fat mass; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; FPG: fasting plasma glucose; HOMA-IR indicates homeostasis model assessment for insulin resistance; hs-CRP: high-sensitivity C-reactive protein.