The Efficacy and Safety of the Chinese Herbal Formula, JTTZ, for the Treatment of Type 2 Diabetes with Obesity and Hyperlipidemia: A Multicenter Randomized, Positive-Controlled, Open-Label Clinical Trial

Table 3

The changes in patients’ symptoms.

	JTTZ group	Metformin group	values
Total symptom score
Week 0	11.03 ± 4.93	10.78 ± 4.63	0.598
Week 12	5.80 ± 4.05	8.57 ± 4.40	0.000
Week 12–week 0	−5.23 ± 4.20	−2.21 ± 4.11	0.000
Paired sample t-test ()	0.000	0.000
Symptom disappearance rate
Thoracoabdominal distension	55 (44.4%)	35 (27.8%)	0.006
Abdominal fullness	74 (54.8%)	52 (46.0%)	0.168
Constipation	62 (72.9%)	26 (31.7%)	0.000
Dry mouth	55 (33.7%)	41 (25.9%)	0.128
Bitter mouth	49 (41.2%)	33 (28.4%)	0.041
Halitosis	46 (45.1%)	18 (21.7%)	0.001
Thirst and drinking cold water	35 (29.4%)	28 (25.0%)	0.453
Increased eating with rapid hunger	57 (46.7%)	33 (30.8%)	0.014
Red tongue and yellow tongue coating	51 (29.8%)	28 (18.8%)	0.023
Power and rapid pulse	71 (50.0%)	34 (27.6%)	0.000